Tissue Lysates
Cayman Chemical SynthetIc KhasInIn 1mg
A steroidal glycoside with diverse biological activities; reduces the proliferation of LNCaP and T47D cancer cells (IC50s = 32.1 and 27.5 µM, respectively); inhibits TNF-α-induced nuclear translocation of NF-κB in HaCaT keratinocytes at 50 nM; decreases AST serum levels in a mouse model of carbon tetrachloride-induced liver injury at 0.1 mg/kg; topical administration reduces EAr epidermal thickness and scaling, as well as leukocyte and macrophage infiltration, in an imiquimod-induced mouse model of psoriasis at 5 mg/kg
Cayman Chemical ProcynIdIn B3 1mg
A polyphenol flavonoid dimer with diverse biological activities; inhibits Aβ42 aggregation (IC50 = 3.54 μM); destabilizes preformed Aβ42 fibrils (EC50 = 5.12 μM); reduces oxidation of linoleic acid and scavenges DPPH free radicals in cell free assays at 1 mM; inhibits hydrogen peroxide-induced production of iNOS and apoptosis in primary murine chondrocytes; reduces chondrocyte apoptosis, pseudocapsule thickness, and the frequency of ectopic cartilage formation in a mouse model of surgically induced osteoarthritis at 0.01 mg/kg
Cayman Chemical SynthetIc GW 9662 1mg
The peroxisome proliferator-activated receptor γ (PPARγ) is the nuclear receptor responsible for transducing the therapeutic activity of the thiazolidinediones. Thiazolidinediones are a group of structurally related synthetic PPARγ agonists with antidiabetic actions in vivo. Rosiglitazone (BRL 49653) is a prototypical thiazolidinedione and has served as a reference compound for this class. There are many PPARγ agonists, including 15-deoxy-.DELTA.12,14-prostaglandin J2 and azelaoyl PAF, which are naturally derived. However, only a few antagonists have been reported. GW 9662 blocks the PPARγ-induced differentiation of monocytes to osteoclasts by >90% at a dose of 0.1 µM. It is therefore a much more potent antagonist than BADGE, which is another reported PPARγ antagonist.
American Research Products Inc CELL MITOCHONDRIAL COMPLEX V F
5000265766 CELL MITOCHONDRIAL COMPLEX V F
American Research Products Inc CELL MITOCHONDRIAL COMPLEX III
5000265142 CELL MITOCHONDRIAL COMPLEX III
Cayman Chemical MItochondrIal FUSN PROMTR 10mg
A promoter of mitochondrial fusion; induces elongation of mitochondria in Mfn1-/- or Mfn2-/- MEFs (EC50s = 5.3 and 4.42 µM, respectively); protects against MPP+-induced mitochondrial fragmentation and cytotoxicity in SH-SY5Y cells at 5 µM; reduces apoptosis and inhibits decreases in testosterone levels induced by triphenyl phosphate in TM3 cells at 1 µM; improves novel object recognition deficits in a rat model of doxorubicin-induced chemobrain at 2 mg/kg
Cayman Chemical MItochondrIal ComP I AcTV 10mL
An MC1R antagonist (IC50 7.23 nM) selective for MC1R over MC2R (IC50 10000 nM) but does antagonize 5-HT2B and 5-HT1A receptors (IC50s 9.66 and 16.9 nM respectively) inhibits MCH-induced [35S]GTPYS binding and calcium influx in HEK293 cells expressing human MC1R at 3 nM reduces stress-induced decreases in the time spent in the open arms of the elevated plus maze in mice at 1 3 and 10 mg/kg decreases immobility time in the forced swim test in mice
Cayman Chemical MItochondrIal PT Pore asy K
Determine mitochondrial inner membrane permeability through the measurement of mitochondrial membrane potential and membrane integrity
American Research Products Inc Rabbit Parathyroid hormone PT
Rabbit Parathyroid hormone PTH ELISA Kit from CUSABIO Detection Range 7 8 pg/mL-500 pg/mL Sensitivity 1 95 pg/mL Sample serum plasma Method Sandwich
Biotium Mammaglobin (SCGB2A2) (Breast Cancer Marker) (MGB1/2000), CF568 conjugate, 0.1mg/mL
Mammaglobin is a 93 amino acid glycoprotein with homology to other secretoglobin-uteroglobin family members. It was originally identified as a breast cancer restricted biomarker by differential screening. Mammaglobin related to secretoglobin family that includes human uteroglobin and lipophilin. Mammaglobin antibody stains cytoplasm of normal breast epithelial cells as well as primary and metastatic breast carcinomas. Mammaglobin expression is absent in prostate, kidney, colon, rectum, small intestine, stomach, pancreas, lung, and thyroid tissues. Mammaglobin may be used as part of an immunohistochemical panel for determination of metastatic breast carcinoma and tumor of unknown primary origin.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, beca
Innovative Research Inc Cow Parathyroid Hormone Kit
Bovine Parathyroid Hormone ELISA Kit - This Kit from Innovative Research is intended for the quantitative determination of this Hormone in biofluid samples, such as serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other fluids. This is a competitive ELISA in strip well format with reagents for up to 96 tests . PTH present in samples reacts with an anti-Bovine PTH monoclonal capture antibody or antigen coated and dried on a microtiter plate. Then, PTH conjugated to biotin competes with the antigen in the sample to bind the capture antibody/antigen. Unbound conjugate and sample antigen is washed away and bound conjugate is then reacted with avidin conjugated to horseradish peroxidase. TMB substrate is used for color development at 450nm. Color development is inverse proportional to the concentration of active PTH. RUO
Biochain Institute Inc Total Protein - Human Adult Normal Tissue: Vagina, 1 mg/PK
Tissue total protein is prepared from whole tissue homogenates. It presents a consistent pattern on SDS-PAGE analysis. The total protein is stored in a buffer with protease inhibitor cocktail, and provided at a concentration of 5 mg/ml.
Biochain Institute Inc Total Protein - Human Tumor Tissue: Esophagus, 1 mg/PK
Tissue total protein is prepared from whole tissue homogenates. It presents a consistent pattern on SDS-PAGE analysis. The total protein is stored in a buffer with protease inhibitor cocktail, and provided at a concentration of 5 mg/ml.